High Deliverability. Low Bounce Rate. Anti-Spam.
In order to reach your audience, you need your campaign to actually reach their email.
Simple logic, right?
Only internet & email providers protect their clients from spam by blocking emails they consider spam. Sending to large number of people will probably put you on that list.
That is why sending your campaigns via a system like inwise ensures maximum campaigns reaching your audience, by providing high deliverability (largest number of people receiving your campaigns), low bounce rate (returning emails failed to reach their destination), and anti-spam technology (making sure your email is not marked as spam).